कैप्टन श्रीनिवास मूर्ति केंद्रीय आयुर्वेद अनुसंधान संस्थान, चेन्नई
Captain Srinivasa Murthy Central Ayurveda Research Institute (CSMCARI), Chennai, Tamil Nadu
1.About the Institute
Captain Srinivasa Murthy Central Ayurveda Research Institute (CSMCARI), Chennai is a prominent institution under the Central Council for Research in Ayurvedic Sciences (CCRAS), Ministry of Ayush, Government of India. It is dedicated to advancing research in Ayurveda and promoting indigenous systems of medicine.
The institute was named after Captain Dr. G. Srinivasa Murthy, a legendary figure in Indian medicine. His disciple, Dr. V. Narayana Swamy, founded the institute, initially named as Captain Srinivasa Murthy Drug Research Institute for Ayurveda (CSMDRIA) in the year 1963 in IMPCOPS, Chennai, with a motive to study the phytochemical aspects of medicinal plants used in Indian Systems of Medicine. Later, the Central Council for Research in Indian Medicine and Homeopathy had taken over this Institute as grant-in-aid. In the year 1979, this Institute became a part of the Central Council for Research in Ayurvedic Sciences (formerly Central Council for Research in Ayurveda and Siddha).
This Institute is currently situated in a land area measuring 7,200 sq. ft, in the Arignar Anna Hospital Campus, Arumbakkam, Chennai with Chemistry, Biochemistry, Botany/ Pharmacognosy, Pharmacology, Microbiology, Pharmacy departments and a Library section. Activities of this institute had diversified to various aspects of research in Ayurveda and Indian Systems of Medicine. Also concentrates on formulating SOP and drug standardization of medicines belonging to Ayurveda. Besides, the Institute has an animal house facility approved by the Committee for Control and Supervision of Experiments on Animals (CCSEA), Ministry of Environment and Forest, Government of India, to conduct animal studies. The institute also houses an indexed regional herbarium facility, Captain Srinivasa Murthy Herbarium (CSMH). This institute is accredited with NABL, licensed Drug Testing Laboratory (DTL) and recognised Ph.D centre. The institute continues to contribute to the development and standardization of Ayurvedic medicines and practices, fostering innovation and excellence in the field.
1.2. Vision and Mission
- To promote research, drug standardisation and training in the field of Ayurveda and traditional medicine.
- To establish Pharmacopoeial monographs and technical dossiers for the Indian Systems of Medicine
- To maintain excellence in testing services as per national/international standards.
1.3. Eponymy: Legacy and inspiration behind our name
Vaidya Ratna Captain Dr. G. Srinivasa Murthy (1887–1962)
Captain Dr. Gorur Srinivasa Murthy was a visionary physician, scholar, and reformer whose pioneering efforts laid the foundation for current scientific study of Indian systems of medicine. Born in Haltore village in Hassan District, he was an outstanding student who earned degrees in Arts, Medicine, Law, and Sanitary Engineering, winning the Chipperfield and Johnstone Gold Medals for general proficiency. Despite no formal training in Sanskrit, he delivered the Presidential Address of the All India Ayurvedic Congress (1924) in proficient Sanskrit. It was a proof to his erudition and devotion to India’s heritage.
After joining the State Medical Service in 1912 – where he served in various capacities – and serving as a Captain in the Indian Medical Service during World War I – where he offered his services in many military hospitals across India -, he combined discipline with deep compassion for healing. His collaboration with the Usman Committee, formed to recognize and encourage indigenous medical systems, led to his seminal work “The Science and Art of Indian Medicine”, which inspired the establishment of the School of Indian Medicine at Kilpauk in 1925, where he served as the first Principal and founded the Integral System – a system that integrate the strengths of both Ayurveda and Allopathy. As a dedicated teacher and institution-builder, he trained generations of practitioners. The School of Indian Medicine conferred him a Diploma in LIM (Licentiate in Indian Medicine) and a Post Graduate degree in Indian Medicine (HPIM – Higher Proficiency in Indian Medicine). A Theosophist influenced by Dr. Annie Besant, he later directed the Adyar Library (1934–1954), elevating it into a premier institution. After retirement, he founded IMPCOPS (Indian Medical Practitioners Co-operative Pharmacy & Stores) in 1944 to ensure the production of authentic Ayurvedic, Siddha, and Unani medicines under hygienic and standardized conditions, which carries his legacy even today.
Honoured with the title Vaidya Ratna during King’s Birthday Honors of 1932, Captain Murthy embodied purity, simplicity, and selfless service. His disciple Dr. V. Narayanaswamy founded this institute in 1963 to perpetuate his ideals. His life remains a shining example of dedication, leadership, and scholarship. We offer our respects to the memory of an extraordinary individual and a dedicated Karmayogi.
1.4. Institute history in brief
Captain Srinivasa Murthy Central Ayurveda Research Institute (CSMCARI), Chennai, traces its origin to 1963 when it was established as the Captain Srinivasa Murthy Drug Research Institute for Ayurveda (CSMDRIA) by Dr. V. Narayanaswamy, a student and colleague of Dr. G. Srinivasa Murthy, a legendary figure in Indian medicine. Supported by Dr. C. Dwarakanath, then Advisor (ISM), Ministry of Health, and with infrastructural assistance from Indian Medical Practitioners’ Co-operative Pharmacy and Stores Limited (IMPCOPS), the institute was inaugurated on 10 January 1963 by the Union Health Minister, Dr. Sushila Nayar. Initially functioning within IMPCOPS, the institute focused on research in phytochemistry and pharmacognosy under Dr. Narayanaswamy’s leadership, studying regionally significant medicinal plants. The Department of Biochemistry was added in 1967, marking the start of vigorous phytochemical studies that led to the development of Imbural tablets, an antitubercular and haemostatic formulation.
A standardization Unit for Ayurveda was established in 1970, leading to the standardisation of 446 formulations from the Ayurvedic Formulary of India. In 1972, the institute was brought under the Central Council for Research in Indian Medicine and Homoeopathy (now CCRAS). In 1974, a pharmacy for Ayurveda and Siddha preparations was added, and in 1977, the institute was affiliated with the University of Madras for Ph.D. research. Under Dr. K.K. Purushothaman’s leadership (1972–1988), the institute published over 150 research papers. To accommodate its growing research activities, the Tamil Nadu Government allotted two floors (9600 sq. ft.) in the Arignar Anna Hospital Campus, Chennai, where the institute was shifted in 1977.
Later, a separate land measuring 7200 sq. ft. was acquired for expansion on the recommendation of the Director of Indian Medicine, Government of Tamil Nadu. A new building was constructed on this land, and in 2013, the institute moved into its present premises within the Arignar Anna Government Hospital of Indian Medicine campus, Arumbakkam, Chennai.
The institute underwent several transformations. It was renamed as Captain Srinivasa Murthy Research Institute for Ayurveda and Siddha Drug Development (2009), later as Captain Srinivasa Murthy Regional Ayurveda Drug Development Institute (2017), and finally as Captain Srinivasa Murthy Central Ayurveda Research Institute (CSMCARI). Now functioning under the Ministry of Ayush, Government of India, the institute has six departments: Ayurveda, Pharmacology, Chemistry, Biochemistry, Microbiology, and Botany/ Pharmacognosy. The institute continues its legacy of six decades as a pioneering institute for Ayurvedic drug research and academic excellence.
1.5. Organizational Chart
1.6. Services Offered
The institute offers a comprehensive suite of services that caters to both regulatory requirements and academic training. These services are designed to support manufacturers, researchers, students, etc., engaged in the development and validation of ASU drugs.
1. Testing and evaluation of ASU Drugs
a. Shelf-life and stability studies: These assessments determine the optimal storage conditions and expiration timelines of ASU formulations, ensuring consumer safety and product reliability.
b. Botanical and pharmacognostic identification and authentication: The institute conducts microscopic and macroscopic evaluations of fresh/ dry/ mounted plant specimens and raw drugs to verify botanical identity for authentication of the plant and to detect adulteration. Herbarium vouchers can also be deposited in the institute regional herbarium.
c. Physicochemical analysis: A wide range of tests are performed to evaluate parameters such as pH, moisture content, ash values, extractive values, and other quality indicators.
d. Safety and efficacy studies: Preclinical evaluations are carried out using validated models to assess the therapeutic potential and toxicological profile of ASU drugs.
e. Microbial testing: These include assays for microbial load, heavy metals, aflatoxins, and other contaminants, ensuring compliance with pharmacopoeial standards.
2. Academic and skill development programs
a. Internship Training: The institute offers a well-structured Internship Training Programme aimed at equipping undergraduate and postgraduate students with practical exposure to traditional medicine research and laboratory practices. The programme is delivered in two formats: a short-term 15-day training module, one month and 3-month training module. These modules are designed for students seeking a concise yet intensive introduction to ASU drug testing, covering multiple disciplines.
b. Project-based internship: The project-based internship, typically spanning 4 to 8 weeks, is tailored for students undertaking academic research or fulfilling curriculum-based project requirements. Interns engage in supervised research activities such as shelf-life studies, microbial load analysis, pharmacological studies and instrument-based evaluations. They are encouraged to formulate research questions, collect and interpret data, and present their findings through structured reports and presentations.
c. Hands-on training on sophisticated instruments: The institute also offers specialized training modules on advanced analytical instruments such as High-Performance Liquid Chromatography (HPLC), Gas Chromatography- Mass Spectrometer (GC-MS), UV-Visible Spectrophotometry, Fourier Transform – Infra red (FT-IR), Induction Coupled Plasma – Organic Emission Spectrophotometer (ICP-OES), Atomic Absorption Spectrophotometer (AAS), Flame Photometer, High Performance Thin Layer Chromatography (HPTLC), Arc HPLC, RT- PCR, Thermal Cyclers (PCR), Hematology analyser, Clinical Chemistry auto analyser, ELISA Reader, Multimode reader and others.
2. Human Resources
| Dr. S. Chitra – Assistant Director-In-Charge |
| Technical |
| Ayurveda/ Pharmacy |
| Dr. G. Kusuma – Research Officer |
| Dr. Soumya MC – Research Officer |
| Pharmacology |
| Dr. R. Arunadevi – Research Officer |
| Ms. N. Monika – Assistant Research Officer |
| Smt. M. Thenmozhi – Assistant Research Officer |
| Smt. K.C. Haritha Yadav – Assistant Research Officer |
| रसायन विज्ञान |
| Dr. Vinod Kumar Thallada – Research Officer |
| Dr. Kousik Ghosh – Research Officer |
| Shri M. Prathapa Reddy – Assistant Research Officer |
| Smt. Maheswari B – Research Assistant |
| Shri V. Naresh – Research Assistant |
| Smt. C. Shakila – Laboratory Attendant |
| सूक्ष्म जीव विज्ञान |
| Dr Swamy C.T – Research Officer (Microbiology) |
| Shri Ravi Prakash Shaliwal – Assistant Research Officer (Biotechnology) |
| Shri R. Raghul Gandhi – Laboratory Attendant |
| Botany/ Pharmacognosy |
| Shri Vishnu Walsan – Research Officer |
| Shri C. Prem Kumar – Assistant Research Officer |
| Dr Akansha Pandey – Research Assistant |
| Biochemistry |
| Dr Anshu Wali – Research Assistant |
| प्रशासन |
| Smt. E. Nagalakshmi – Private Secretary |
| Shri Balaji B. – Upper Division Clerk |
| Support Staff |
| Shri R. Loganathan – Multi Tasking Staff |
Employee details : Annexure I
Biodata of officers and staff : Annexure II
3. Communication & Publicity
Suo Moto Disclosures : Annexure III
Hindi Magazine : Annexure IV
4. Research & Development:
In its early stages, the institute focused on three key research areas: cancer research, family welfare programs, and malaria research. Several anti-cancerous principles have been isolated from medicinal plants, such as solamarine from Solanum trilobatum and plumbagin from Plumbago zeylanica.
At present, the institute is actively engaged in Ayurvedic research in various disciplines across three broad areas – Medicinal Plant Research, Drug Standardization Research and Pharmacology Research. The focus is on the development and scientific validation of Ayurvedic formulations and single-plant-based medicines.
More than 600 research papers have been published in various national and international journals, 15 book chapters and about 154 scientific papers have been presented in various scientific seminars, conferences and symposia. The work carried out in CSMCARI has been included in the various publications of the Department of AYUSH and ICMR. Research activities confer various departments have been described below. The status of ongoing and completed projects (IMR/EMR) mentioned pertains to last 10 years.
Publication List : Annexure V
4.1. Medicinal Plant Research
Medicinal Plant Research (MPR) at CSMCARI, Chennai, is executed by two departments – Botany/ Pharmacognosy and Pharmacy.
Department of Botany/ Pharmacognosy
Department of Botany/ Pharmacognosy conducts research and provides testing services in various areas related to the identification, authentication, and development of quality standards of medicinal plants and raw drugs used in Ayurveda.
To date, the department has contributed around 50 research publications in national and international journals and successfully completed seven intramural research projects. Four intramural research projects are currently ongoing, focusing on ethnobotany of Kolli and Pachamalai hills, and development of quality standards of drugs used in Ayurveda and traditional medicine. Monographs prepared by the department have been incorporated into the Ayurvedic Pharmacopoeia of India (API) and the Ayurvedic Formulary of India (AFI). The department has developed and published 15 powder monographs in API Part-I, Vol. VIII (2011), 8 Comprehensive Technical Dossiers on single drugs, 117 monographs for Quality Standards of Indian Medicinal Plants (published by ICMR). The department has also carried out studies on several compound formulations including Nimbadi Kwath Curna, Trikatu Curna, Sunthi Guggulu, Gomutra Haritaki, AYUSH-A, AYUSH-D, AYUSH Herbal Tea, and AYUSH M3.
The department also hosts an NABL-accredited laboratory which provides testing services under four parameters: macroscopic identification, sectional studies, powder microscopy, and taxonomic identification of Ayurvedic drugs. Since 2008, the department has been maintaining NABL Accreditation as per ISO/IEC 17025: 2017, adhering to NABL Standards. It is also recognized as a Drug Testing Laboratory (DTL) by the State Government of Tamil Nadu.
Captain Srinivasa Murthy Herbarium (CSMH), the regional herbarium under the department, which houses accessions dating back to 1960, is internationally indexed under Index Herbariorum of New York Botanical Garden, with the acronym “CSMH”. The department provides internships, training, and assistance for dissertations and research projects of post-graduate students. The department is equipped with sophisticated instruments, including High-Performance Liquid Chromatography (HPLC), High-Performance Thin Layer Chromatography (HPTLC), deep freezer (-80°C), a Trinocular compound microscope with CMOS camera and drawing tube attachment, a stereo zoom microscope and a flatbed herbarium scanner (1600 dpi).
| Ongoing Projects | Completed Projects |
| 1. Development of Quality standards for Useful Parts of Selected Medicinal Plants of Ayurveda (IPS0033) 2. Development and Digitalization of Authentic Ayurvedic Raw Drugs and Herbarium for the Medicinal Plants Appearing in Ayurvedic Formularies of India in Mandatory Drug Testing Laboratories of CCRAS. (IPS0027) 3. Development of Quality Standards of Elsholtzia Species and assessment of Efficacy in Gastric Inflammatory Conditions (CPS0002) 4.Medico-Ethnobotanical Surveys in Kolli Malai and Pacha Malai and preparation of Monographs. (IBO0066) | 1. Developing Pharmacognostical Standards for some Ambiguous Ayurvedic Drugs (Sandigdha Dravyas) appearing in the Ayurvedic Formularies, Parts I to III. (IPS0013) 2.Pharmacognostical Evaluation of Medicinal Plants cited in Ayurvedic Formulary of India excluding the plants mentioned in Ayurvedic Pharmacopoeia of India- Part –I 3.Pharmacognostical Evaluation of Medicinal Plants cited in Ayurvedic Formulary of India excluding the plants mentioned in Ayurvedic Pharmacopoeia of India- Part –II. (IPS0014) 4..Photographic Atlas on Macro-microscopic Characteristics of Medicinal Plants Listed in Ayurvedic Pharmacopoeia of India, Part-I, Volume – II. (IPS0019) 5.Development of drug Master file and dossier on Fruits of Emblica officinalis (Farm: Phyllanthaceae) for Important Promising Medicinal Plants Based on Leads from Ayurveda & Contemporary Research. (IPS0027) 6.Development of Quality Standards of Selected Extra-pharmacopoeial Drugs (Anukta Dravyas) Used in Local Health Traditions Collected from Different Regions of India. (IPS0028) 7.Anthology of Pharmacognostical Research Outcomes of CCRAS on Selected Medicinal Plants of Ayurveda. |
Department of Pharmacy/ Ayurveda
The pharmacy department of CSMCARI possesses a pharmacy section and a machinery room. This department is actively engaged in Developing Quality Standards for crude drugs and in developing Standard Operating Procedures for various Ayurvedic formulations. The pharmacy section is equipped with a Pill-making machine, a distillation unit, an End-runner mill, a fermentation vessel, a Tray drier, a Laboratory Blender, a Membrane filter with a vacuum pump, and a Capsule-filling machine. The machinery room is installed with Mini pulveriser (for making curnas), a disintegrator (for making kasayam powders) and a jaw-crusher (for disintegrating very hard plant parts like heart-wood, root and bark).
Ayurvedic drugs are mainly based on plants and plant-based products, besides animal products, metals/minerals and marine origin drugs (Sudha-varga drugs). In the Ayurvedic Drug manufacturing industry, there is a significant increase in information on Ayurvedic drugs and identification of constituents of drugs, parts used, method of preparation and standardisation of products. At the same time, new problems have also emerged in this sector, like non-availability of some of the constituent drugs, especially the root and bark of several plants., increase in demand of Ayurvedic drugs leading to substitution/adulteration, imposition of new laws to protect the environment as well as various plant species and formulations like Curnas (Powders), Bhasmas (metallic preparations), Asavas, Aristas (Alcoholic preparations), according to classical methods. Realising these problems in the supply of raw material, there is a need to facilitate the availability of raw drugs, which are authentic and contain the essential components as required under the Pharmacopoeial Standards. Keeping these facts in view since inception to 2023, the Pharmacy department is working in this research area and has taken up steps to develop Quality standards for plants, animals and mineral origin drugs and develop Standard Operating Procedures for processing to improve the quality of the final product.
The department is also concentrating on ethno-medicinal survey studies (2014-2017). Currently working on developing quality standards for extra-pharmacopeial drugs and Arka formulations and involved in organising medical camps at various places. The department is also acting as the facilitating centre to other departments of the institute, in selecting suitable drugs for research projects. So far, SOPs have been developed for 65 Ayurvedic formulations.
| Ongoing Project | Completed Project |
| Developing Quality Standards for selected Arka Formulations | Ethno-medicinal Survey of Plants Used in Various Diseases by Tribe of Thandarai, Chengalpattu, Kancheepuram District, TamilnaduDeveloping Quality Standards for selected Extra-pharmacopoeial drugs collected from Irula tribes of Thandarai, Kancheepuram District, Tamilnadu.Documentation of Life Profiles of Luminaries of Ayurveda – Vaidyaratna Captain G Srinivasa MurthyDocumentation of Life Profiles of Luminaries of Ayurveda – Ms Savita SatakopanDocumentation of Life profiles of Admirable Personalities to Transform Ayurveda (APTA)’- Padmashri Dr.V.Narayanaswamy.Documentation of Life Profiles of Luminaries of Ayurveda – Vaidyaratna N Rama VarierDocumentation of Life profiles of Admirable Personalities to Transform Ayurveda (APTA)’- Aryavaidyan P V Raghava Varier |
4.2. Drug Standardization Research
Drug Standardisation Unit was established in the year 1979 as a separate project for the Standardization of Siddha drugs. This was consequent to the bifurcation of Central Council for Research in Indian Medicine & Homeopathy into separate Councils in March 1978. Later this unit got merged with the Chemistry department of CSMCARI Chennai.
Department of Chemistry
The department comprises two sections: Analytical and Phytochemical. The Analytical section focuses on standardizing Ayurvedic drugs based on pharmacopoeial parameters. It has completed 446 formulations in Part I and Part II of the Ayurvedic Formulary of India. Standards for individual ingredients used in compound preparations are also being developed. The Phytochemical section investigates the chemistry of medicinal plants through extraction, fractionation, and isolation of known and novel compounds, followed by structural identification and biological screening. Notable bioactive compounds include Solamarine, Gangetin, Vicolides A–D, Physalin D, Arbortristosides A & B, Echitamine chloride, Plumbagin, Cryptanoside-A, Oleanolic acid D-glycoside, and Ruberythric acid. A key achievement is the isolation of an alkaloidal glucoside from Solanum trilobatum, patented and under commercial development for use as a cancer treatment adjuvant.
Since 2008, the department has been maintaining NABL Accreditation as per ISO/IEC 17025: 2017, adheres to NABL Standards. It is also recognized as a Drug Testing Laboratory by the State Government of Tamil Nadu to carry out the drug testing for industries/academic institutes/laboratories etc. In addition to sample testing, the department has been conducting cutting-edge research in the Indian system of medicine, especially, in Ayurvedic sciences. The department has equipped with sophisticated analytical instruments like GC-MS, ICP-OES, HPLC, HPTLC, AAS, Flash chromatography, Flame photometry, UV-Vis spectrophotometer, FT-IR, Rotary evaporator, milli-Q water system, Polarimeter, and other minor equipment. The Department mainly carries out preliminary phytochemical and physicochemical analysis, isolation of chemical markers and their elucidation, development of TLC/HPTLC fingerprint profile, estimation of markers and phytochemicals in single drug as well as compound formulation of herbal drugs, estimation of heavy metals, and identification of adulterants using analytical techniques.
| Ongoing Project | Completed Project |
| Development of quality standards & SOP with marker-based analysis and shelf-life study of four medicinally important classical ayurvedic formulationsIsolation of Marker Compounds and Development of Marker Compound Library from four Selected Ayurvedic Medicinal Plants (Kancanara, Asthisrnkhala, Puskara & Lajjalu)Phytochemical investigation of hydro-alcoholic extractives with different ratios of selected Kvatha formulations Pharmaceutical Development and Standards for Formulation AYUSH-64 (Duration: 03 year, 2021-2024) Development of Quality Standards, Estimation of Markers, and Shelf-Life Study of Kvatha Curna Formulations (Duration: 03 years) 2023-2026 Evaluation of Seasonal and Geographical Variation on Phytoconstituents/Marker Compounds in Selected Ayurvedic Medicinal Plants (Duration 02 years) 2023-2025. Comparative phytochemical evaluation of Ht.Wd. with small branches, leaf, and st.bark of common medicinal plants used in Ayurveda (Duration 02 years) 2024-2026. Nutritional profiling, Estimation of marker of Balya Drugs’’ Development of Quality Standards of Selected Extra-Pharmacopoeial Drugs (AnuktaDravyas) used in Local Health Traditions collected from different regions of India.Development of Quality Standards, Estimation of Markers and Accelerated Shelf-Life Studies of Guducyadi, Caturbhadra and Amrtottara Kvatha Curna Formulations.आयुर्वेदिक पौधों से मार्कर कंपाउंड का अलगाव और मार्कर कंपाउंड लाइब्रेरी का विकास | Estimation of Calcium and Trace minerals in Sudhavarga drugs of Ayurveda.Formulation of Drug Master File and Dossier for important promising medicinal plant Emblica officinalis (Phyllanthaceae) based on leads from Ayurveda and contemporary researchPharmacognostical Evaluation of Medicinal plants cited in Ayurvedic Formulary of India, Excluding the plants mentioned in API” Part-II” |
4.3. Pharmacological Research
Pharmacological research at CSMCARI, Chennai, is executed by pharmacology, biochemistry and microbiology departments.
Department of Pharmacology
The Pharmacology department is specialized in conducting Pre-clinical toxicity and biological activity evaluation studies of various Ayurvedic formulations. The department has CCSEA (M/o Fisheries Animal Husbandry and Dairying, Government of India) approved Animal House Facility (Reg.No. 591/GO/Re/S/02/CPCSEA) with the total area of 4200 sq. ft. The Department is NABL Accredited as per ISO/IEC 17025:2017 for veterinary testing of hematology samples. Also recognised as a Drug Testing Laboratory by the State Government of Tamil Nadu to carry out the drug testing for industries/academic institutes/laboratories etc and also extending services to scholars and researchers. The lab is equipped with ELISA reader for immunology and hormonal assays, activity cage for excitatory and depressant activity, swimming test apparatus for inducing stress and stress induced ulcerogenic potential studies, metabolic cages for measuring feed and water intake, urine and faecal matter collector, diuretic activity testing, Y maze, plus maze for nootropic activity, histamine chamber for anti-asthmatic activity, veterinary haematology analyser, UV spectrophotometer, Stereo zoom microscope, ECG monitoring, power lab with lab chart software, millar catheter for invasive blood pressure monitoring, CODA monitor for NIBP, Arc HPLC with Empower3 software and nitrogen evaporator for pharmacokinetic studies. In Histopathology facility, the instruments like microtome, hot air oven, incubator are present. The Animal house Facility has a barrier system under CCTV monitoring which contains clean and service corridors equipped with air shower, pass boxes, air handling units, Industrial size Autoclave, RO water facility, UV room for surface sterilization. Isoflurane anaesthesia system is available for small animal procedures and carbon dioxide chamber for animal sacrifice. The Department have MoU with Tamil Nadu Biomedical Waste Management System for biological waste disposal. The department carries out work under Council allotted projects; CCRAS Intramural Research Projects which includes pre-clinical toxicity screening following OECD as well as CCRAS guideline along with other appropriate guidelines such as ICH, EMA etc., and efficacy studies, Collaborative projects with CSIR-IITR Lucknow, ICMR- NIN Hyderabad and many Ph. D. Projects. The department has published several papers in indexed and other reputed journals; received many awards, medals and participated in Oral and Poster presentations in National and International Conferences, Seminars/workshop and scientific meetings as invited and lead speakers. This Institute is affiliated with University of Madras, produced one PhD and currently two scholars are pursuing Ph D in the Department. The staff worked on Ayurvedic formulations such as Parpati, Churna, Vati, Lehya, Bhasma, Guggulu, Extracts, External applications, Single drugs and Eye drops. The department has expertise on animal models like Asthma, Arthritis, Nephropathy, Migraine, Anti-inflammatory, Ocular testing, Surgical model of stroke and Obesity.
| Ongoing Projects | Completed Projects |
| Cardioprotective Effect of Pushkara Guggulu on Experimentally Induced Myocardial Infarction in Rats, instruments purchased, order placed for procurement of animals. Development of Madhuca longifolia (Flower) based food recipe (Product development) and its nutritional,toxicity, efficacy and bioavailability studiesToxicity profile of Tribhuvana Kirti Rasa in experimental animals.Development of Opuntia elatior (fruit) based food recipes (product development) and its nutritional, toxicity, efficacy and bioavailability studies Acute and chronic (180 days) oral toxicity study of coded drug AYUSH RPAcute and Chronic (180 days) repeated dose oral toxicity study of NimbatitkamAcute and 180-days repeated dose oral toxicity study of Ayush Balrakshak Lehyam | Effect of Haritkadi yoga on middle cerebral artery occlusion ischemic-reperfusion injury and its safety in rats.Acute and 90 days repeated dose oral toxicity study of Coded drug AYUSH-PK AvalehaAcute and 90 days repeated dose oral toxicity study of Coded drug AYUSH-SDM.Development of Drug Master file and Dossier on fruit of Emblica officinalis for promising medicinal plants based on leads for Ayurveda and contemporary research. Pharmacology part.Evaluation of Sveta Parpati for its curative and preventive action in Urolithiasis experimental study in rats.Preclinical Evaluation (Toxicity and efficacy profile) of an Ayurvedic herbal formulation Vaisvanara Churna used in the treatment of Rheumatoid arthritis.Acute and 90 days repeated dose oral toxicity study of Coded drug AYUSH-HRIn vitro and in vivo nephro protective evaluation of AYUSH K1 extract. In-vitro and in-vivo evaluation of anti-migraine activity of AYUSH-M3.Safety and anti-obesity activity of Tryusanadi guggulu in experimental animals. |
Department of Biochemistry
Department of Biochemistry was established in 1967. Currently, it is housed on the first floor of the Captain Srinivasa Murthy Central Ayurveda Research Institute, Arumbakkam, Chennai. This department has been accredited with NABL since 2008 with ISO/IEC 17025:2005 and upgraded to ISO/IEC 17025:2017 and strictly follows the NABL norms for quality assurance. This department has good instrumentation facilities. The instruments with periodic maintenance and quality control checks are done regularly to ensure the quality of test results. The department analyses the biochemical aspects of Council allotted safety and efficacy studies and Intra Mural Research projects. This department participates in proficiency testing programs and intra-laboratory comparisons to maintain quality standards. This laboratory is an approved Drug Testing Laboratory for herbal drug analysis by the State Licensing Authority, Indian Systems of Medicine, Government of Tamil Nadu. The deparment supports the postgraduate students for their thesis research work. Several papers have been presented in conferences/seminars and several research articles have been published in well-reputed journals. Besides this, Hands-on training on sophisticated instruments and summer training is regularly provided to undergraduate and postgraduate students from various academic and research institutes. The department was equipped with sophisticated instruments like Clinical chemistry auto analyzer, RT-PCR, Gel Documentation Unit, Western Blot, UV-Visible spectrophotometer, Semi auto analyzer, Tissue homogenizer, Cooling Microcentrifuge, Deep freezer (-20°C), Electrophoresis units, pH meter, Micro centrifuges, Digital Hot top with magnetic stirrer and other accessory instruments.
| Ongoing Project | Completed Project |
| प्रायोगिक चूहों में त्वचा के एपिडर्मल कार्सिनोमा के उपचार में चौलमूग्रा तेल और श्वेता सरशपा चूर्ण की कैंसर विरोधी गतिविधि। | A biochemical role of AYUSH-PTK, an Ayurvedic formulation against anti-tubercular drug-induced hepatotoxicity in rats (2020-2022)Anti-atherosclerotic activity of Hirdayarnava rasa on animal model (2018-2020)Biochemical studies on Premna integrifolia Linn. in high-fat diet-induced atherosclerosis model rats (2014-2016) |
Department of Microbiology
The Department of Microbiology at CSMCARI, Chennai, is an NABL-accredited testing laboratory as per ISO/IEC 17025:2017. Routine testing of AYUSH products and DTL samples are conducted in the department in accordance with API guidelines. Along with research activities involving IMR projects. More than 100 Ayush products/samples are being tested in each financial year under IMR projects, and dissertation training/short-duration training is also being provided to the students. The department is equipped with a BSL-2 facility along with various instruments for research activities such as pH meter, Autoclave Bacteriological and BOD Incubators, colony counter, UV-Chamber, Microplate reader, cooling centrifuge, Trinocular Microscope, Cyclomixer, Magnetic stirrer, refrigerator, -40℃ deep freezer and other supporting instruments.
| Ongoing Project | Completed Project |
| Isolation and Identification of Endophytic Microorganisms from the stem barks used in Ayurveda (Panchavalkala) and Evaluation of their Antimicrobial, antioxidant and antibiofilm activities | Antibacterial Activity of selective Ayurveda formulations against Gastrointestinal infection, Respiratory infection and Urinary Tract infection-causing bacteria |
5. Achievements & Events
About 600 research papers have been published in various national and international journals, and about 150 scientific papers have been presented in various scientific seminars, conferences and symposia. The work carried out in CSMCARI has been included in the various publications of the Department of AYUSH and ICMR, such as the following:
- Pharmacopeial Standards for Ayurvedic Formulations, published by Department of ISM&H, Ministry of Health & family welfare, government of India 1987.
- Quality Control standards for Certain Sidha Formulations, Published by Department of ISM & H, Ministry of Health & Family Welfare, Government of India, 1992.
- The Ayurvedic Pharmacopoeia of India, Part-II, Volume-I, published by Department of AYUSH, Ministry of Health & Family Welfare, Government of India, 2007 (Monograph on 10 Churna)
- The Ayurvedic Pharmacopoeia of India, Part-II, Volume-II, published by Department of AYUSH, Ministry of Health & Family Welfare, Government of India, 2008 (Monograph on 4 Churna)
- Quality Standards of Indian Medicinal Plants, Vol.5, published by Indian Council of Medical Research (ICMR), (Monograph on 7 Plants).
- Quality Standards of Indian Medicinal Plants, Vol.6, published by Indian Council of Medical Research (ICMR), (Monograph on 9 Plants).
- Quality Standards of Indian Medicinal Plants, Vol.7, published by Indian Council of Medical Research (ICMR), (Monograph on 11 Plants).
- Quality Standards of Indian Medicinal Plants, Vol.8, published by Indian Council of Medical Research (ICMR), (Monograph on 10 Plants)
- Quality Standards of Indian Medicinal Plants, Vol.10-17, published by Indian Council of Medical Research (ICMR), (Monograph on 80 Plants)
5.1. Approvals
1. Committee for the Control and Supervision of Experiments on Animals (CCSEA) Approval: The Institute’s Animal house facility was approved by Committee for the Control and Supervision of Experiments on Animals (CCSEA) in the year 2002.
2. Drug Testing Laboratory: The drug Controller of Tamil Nadu had accorded drug license to this institute for testing Ayurveda and Siddha Drugs in the year 2009. This facility is used by many manufacturers and researchers at large.
3. National Accreditation Board for Testing and Calibration Laboratories (NABL): The institute has been accredited with ISO/IEC: 17025 (General Requirements for the Competence of Testing and Calibration Laboratories) for Chemical (Chemistry Department) and Biological Scope (Botany/Pharmacognosy and Biochemistry) since 2008. Microbiology and Pharmacology are included under Biological scope in 2023. The scope extended to analyse all API parameters.
4. Ph.D. research centre under the University of Madras: Academically, it is a recognized Ph.D. research centre under the University of Madras, having awarded over 40 doctoral degrees since 1979. Currently, 10 students are pursuing Ph.D under various disciplines in this institute.
5.2. Event photographs
| Diamond Jubilee Celebration and International Conference on, “Integrative Approach of AYUSH Medicine in Health Care” held at National Institute of Ocean Technology campus on 6वां & 7वां January, 2023 |
 CME programme for AYUSH Doctors/ Scientists on “Scientific Advancements in Ayush Research and Drug Standardization” held from 18वां to 23तृतीय August 2025 |
 Medical Camp conducted at Sumaithangi Trust, Perumbakkam Chennai on September 2025 |
 Medical Camp conducted at the Institute premises for staff and their family |
 4 days NABL training for CCRAS Officers and Staff conducted in June 2023 |
 GLP training for CCRAS Officers and Staff conducted in July 2023 |
6. Event & Other Activity
 Ayurveda Day Celebrations 2025 |
 Hindi Fortnight Celebration 2025 |
 International Yoga day 2025 |
 World Environment day 2025 |
 National Sports day 2025 |
 Swachatta Hi Seva |
7. Patents and Technology Transfer
The institute claimed 08 patents for various phytochemical isolations.
| क्र.सं. | Patent number | Patent Filed |
| 1. | 140367 | A process for isolation /production of gangetin from डेस्मोडियम गैंगेटिकम D.C. (Fam: Leguminosae) |
| 2. | 140381 | A process for isolation /production of Tomatid-5-3-en ol from Solanum trilobatum Linn. (Fam: Solanacaae) |
| 3. | 140382 | A process for isolation /production of Methylangolensate and Deoxyandirobin from stem bark of Soymida febrifuga A. Juss. (Fam: Meliaceae) |
| 4. | 145857 | A process for isolation /production of Liriodenine-7-oxo-aporphine from the heartwood of Aquilaria agallocha Roxb. (Fam: Thymiliaceae) |
| 5. | 150024 | A process for isolation /production of Vinblastine from Whole Plant (Leaves, Stem, Root) of Vinca rosea Linn. (Fam: Apocynaceae) |
| 6. | 150019 | A process of preparation of vincristine and vinblastine-two anticancer drugs from the whole plant (Leaves, stem, Roots) of Vinca rosea Linn. (Fam: Apocynaceae) |
| 7. | 145858 | A process for the isolation of 9,13-epoxy,6-hydroxy, 8-labdane 6,14,19,20-dilactone known as Nepataefolinol from the whole of Leonotis nepaetaefolia Linn. (Fam: Labiatae) |
| 8. | 147936 | A process for the isolation of 2—hydroxy-3-(3 methyl 1-2 butenyl)-4-napthoquinone, known as Lapachol from the root of Stereospermum tetragonum DC. (Fam: Bignoniaceae) |
8. Accreditation/ Recognition of CCRAS
The institute is a nationally recognized centre of excellence in traditional medicine research, quality assurance, and academic training. Licensed as a Drug Testing Laboratory (DTL) by the Drug Controller of Tamil Nadu (Indian System of Medicine), it is authorised to conduct comprehensive testing of Ayurveda and Siddha (ASU) drugs, validating their safety, efficacy, and quality. The institute has NABL accreditation under ISO/IEC 17025:2017, certifying its technical competence in laboratory testing for 185 parameters, it reinforces its alignment with national quality benchmarks.
The institute’s herbarium is internationally indexed under Index Herbariorum of New York Botanical Garden, with the acronym “CSMH” showcasing its taxonomic precision and relevance to pharmacognostic research. It houses authenticated specimens vital for botanical identification and quality control. The CCSEA-approved animal facility supports ethical preclinical studies, and the institute will be actively pursuing GLP accreditation under NGCMA, ensuring globally accepted standards in non-clinical safety data.
Academically, it is a recognised Ph.D. research centre under the University of Madras, having awarded over 40 doctoral degrees since 1979. This synergy of regulatory testing and academic inquiry positions the institute as a translational research hub, bridging traditional knowledge with modern scientific frameworks.
9. Annual Reports :Annexure VI
10. Statistical Information
| Department | Ongoing Projects | Completed Projects |
| आयुर्वेद | 1 | 3 |
| Botany/Pharmacognosy | 4 | 7 |
| रसायन विज्ञान | 10 | 28 |
| सूक्ष्म जीव विज्ञान | 1 | 1 |
| Biochemistry | 1 | 3 |
| Pharmacology | 7 | 35 |
| कुल | 23 | 77 |
11. Library and publications available for sale
The institute boasts a well-equipped library housing 1,692 books, encompassing a wide range of subjects including Ayurvedic texts such as the Samhita’s, Ayurvedic and Siddha pharmacopoeias, Indian Pharmacopoeia, ICMR quality standards, comprehensive volumes on medicinal plants, and key references and journals in Ayurveda, Botany/ Pharmacognosy. chemistry, Biochemistry, Pharmacology, Microbiology, and related biomedical sciences.
11.1. Publications available for sale
| No | Sales Books Name | Pub | Year | Price | Part | Vol | Stock |
| 1 | Abhinav Chinthamani (HINDI) | सीसीआरएएस | 2009 | 450 | मैं | – | 11 |
| 2 | Abhinav Chinthamani (HINDI) | सीसीआरएएस | 2009 | 450 | II | – | 11 |
| 3 | Application of standardised Namburi phased Spot test in Identification of Bhasma and Sindura Preparations of Ayurveda, 2nd Edition | सीसीआरएएस | 2010 | 130 | – | – | 15 |
| 4 | Aupasargikatantra targata Puyameha Vijnanam | सीसीआरएएस | 2007 | 190 | – | – | 18 |
| 5 | Ayurveda Chikitsa Mariya arogya Grihopacha – ramulu (TELUGU) | CCRS | 2005 | – | – | 20 | |
| 6 | Ayruveda Clinical Methods Series -II Ayurveda Based | सीसीआरएएस | 2021 | 360 | – | – | 5 |
| 7 | Ayurveda Encyclopedia | सीसीआरएएस | 2013 | 820 | मैं | – | 23 |
| 8 | Ayurveda Encyclopedia | सीसीआरएएस | 2013 | 820 | II | – | 24 |
| 9 | Ayurveda Encyclopedia | सीसीआरएएस | 2013 | 820 | III | – | 22 |
| 10 | Ayurveda for Healthy Living Svasthasya Svasthya Raksanam | सीसीआरएएस | 2018 | 503 | – | – | 6 |
| 11 | Ayurveda Sangraha (Hindi) | सीसीआरएएस | 2021 | 1070 | – | – | 0 |
| 12 | Basavarajiyam (English) | सीसीआरएएस | 2013 | 1040 | – | – | 5 |
| 13 | Basic Tenets of Dravyaguna | NIIMH | 2020 | 308 | – | – | 6 |
| 14 | Bhaswarajniyam -HINDI | सीसीआरएएस | 2007 | 733 | – | – | 17 |
| 15 | Brain ageing and Ayurveda | सीसीआरएएस | 2008 | 360 | – | – | 2 |
| 16 | Cakradatta | NIIMH | 2020 | 515 | – | – | 6 |
| 17 | Chakradatta- Ratnaprabha -Bulletin | NIIMH | 2003 | 240 | – | – | 20 |
| 18 | Charak Samhita Nidana Sthana- | सीसीआरएएस | 2021 | 1005 | – | – | 0 |
| 19 | Chikitsarnavah (Vishwanath Chikitsa) – HINDI | सीसीआरएएस | 2010 | 400 | – | – | 15 |
| 19 | Chikitsarnavah (Vishwanath Chikitsa) – HINDI | सीसीआरएएस | 2010 | 400 | – | – | 12 |
| 20 | Cikitsa Prabhakara of Shriprabharar Ogale (English Translation ) | सीसीआरएएस | 2021 | 1000 | – | – | 11 |
| 21 | Clinical Research Protocols for Traditional Health Science | सीसीआरएएस | 2010 | 1400 | – | – | 8 |
| 22 | Clinical Safety Efficacy of Dhatri Laucha Classical Ayurvedic (pandu roga) | सीसीआरएएस | 2010 | 200 | – | – | 10 |
| 23 | Clinical studies of certain Ayurvedic vyanabala Vaisamya | सीसीआरएएस | 2009 | 100 | – | – | 9 |
| 24 | Clinical Studies of Certain Ayurvedic Mutrasmani | सीसीआरएएस | 2008 | 100 | – | – | 1 |
| 25 | Clinical Studies of Certain Ayurvedic Formulations in the Management Paraplegia (PANGU) | सीसीआरएएस | 2010 | 110 | – | – | 12 |
| 26 | Collection and digitization (Descriptive Catalogue) | सीसीआरएएस | 2013 | 780 | – | मैं | 15 |
| 27 | Collection and digitalization (Descriptive Catalogue) | सीसीआरएएस | 2013 | 780 | – | II | 14 |
| 28 | Compendium of Important Cereals | सीसीआरएएस | 2021 | 625 | – | मैं | 5 |
| 29 | Database on Medicinal Plants (used in Ayurveda) | सीसीआरएएस | 2004 | 720 | – | 6 | 0 |
| 30 | Descriptive Catalogue of Medical Manuscripts | सीसीआरएएस | 2010 | 450 | – | मैं | 13 |
| 31 | Descriptive Catalogue of Medical Manuscripts | सीसीआरएएस | 2010 | 450 | – | II | 13 |
| 32 | Descriptive Catalogue of Medical Manuscripts | सीसीआरएएस | 2011 | 450 | – | III | 13 |
| 33 | Exploration of Veterinary Practices in Ayurveda | सीसीआरएएस | 2016 | 850 | – | – | 1 |
| 34 | Guidelines on Basic Training and Safety in Panchakarma | सीसीआरएएस | 2009 | 100 | – | – | 0 |
| 35 | Hand Books of Anupana Pathya & Apathya | NIIMH | 2012 | 295 | – | – | 2 |
| 36 | Hand Book of Common Siddha Kayakalpa | सीसीआरएएस | 2008 | 100 | – | – | 1 |
| 37 | Hand books of Domestic Medicine (URUDHU) | सीसीआरएएस | 2007 | 100 | – | – | 21 |
| 38 | Healing Herbs of Himalaya (HINDI) | सीसीआरएएस | 2008 | 400 | – | – | 8 |
| 39 | Healing Herbs of Himalaya (English) | सीसीआरएएस | 2008 | 400 | – | – | 2 |
| 40 | History and Accounts- Unani Medicine | NIIMH | 2016 | 346 | – | – | 6 |
| 41 | Inventory of Animal Products | सीसीआरएएस | 2008 | 600 | मैं | – | 2 |
| 42 | Inventory of Animal Products | सीसीआरएएस | 2008 | 1000 | II | – | 2 |
| 43 | Local Health Traditions (LHTS) oral health | सीसीआरएएस | 2021 | 2600 | – | – | 6 |
| 44 | Mahamahopadhyaya (Hindi) | सीसीआरएएस | 2021 | 150 | – | – | 4 |
| 45 | Management of Chikungunya | सीसीआरएएस | 2009 | 300 | – | – | 20 |
| 46 | Manual of Standard operative Procedures for Prakriti Assessment | सीसीआरएएस | 2020 | 250 | – | – | 52 |
| 47 | Manual on Geriatric Health Care Through Ayurveda | सीसीआरएएस | 2009 | 200 | – | – | 0 |
| 48 | Marmacikitsa | सीसीआरएएस | 2020 | 700 | – | – | 21 |
| 49 | Medicinal Plants Geriatric Health Care | सीसीआरएएस | 2008 | 120 | – | – | 10 |
| 50 | Metals and Minerals of Ayurveda Proceedings | सीसीआरएएस | 2010 | 100 | – | – | 0 |
| 51 | Quality and Safety of select Rasakalpa | सीसीआरएएस | 2019 | 850 | – | 1 | 8 |
| 52 | Quality and Safety of select Rasakalpa | सीसीआरएएस | 2019 | 395 | – | 2 | 23 |
| 53 | Quality and Safety of select Rasakalpa | सीसीआरएएस | 2019 | 350 | – | 3 | 23 |
| 54 | Quality and Safety of select Rasakalpa | सीसीआरएएस | 2019 | 270 | – | 4 | 23 |
| 55 | Quality and Safety of select Rasakalpa | सीसीआरएएस | 2019 | 250 | – | 5 | 23 |
| 56 | Quality and Safety of select Rasakalpa | सीसीआरएएस | 2019 | 380 | – | 6 | 4 |
| 57 | Quality and Safety of select Rasakalpa | सीसीआरएएस | 2019 | 420 | – | 7 | 4 |
| 58 | Quality and Safety of select Rasakalpa | सीसीआरएएस | 2019 | 520 | – | 8 | 4 |
| 59 | Reported Medical Practices on Prevention | सीसीआरएएस | 2010 | 540 | – | – | 11 |
| 60 | Reported on Screening of Single Herbal Drug | सीसीआरएएस | 2009 | 100 | – | – | 1 |
| 61 | Research Study Profile of Rasamanikya | सीसीआरएएस | 2009 | 230 | – | – | 10 |
| 62 | Safety / Toxicity Study Report | सीसीआरएएस | 2009 | 700 | – | – | 5 |
| 63 | Safety and Prescription Trends of Rasaushadhis – | सीसीआरएएस | 2021 | 795 | – | – | 0 |
| 64 | Sanskrit Medical Manuscripts in India | सीसीआरएएस | 2005 | 300 | – | – | 17 |
| 65 | Select Research Papers on Rheumatoid Arthritis (AMAVATA) | सीसीआरएएस | 2009 | 100 | – | – | 2 |
| 66 | Shalakyatantra Ayurvediya Netraroga Vijnana | NIIMH | 2016 | 740 | – | – | 6 |
| 67 | Sharabharajiyam | सीसीआरएएस | 2007 | 207 | – | – | 18 |
| 68 | Svasthya Assessment Scale (SAS) | सीसीआरएएस | 2020 | 470 | – | – | 12 |
| 69 | Text Book of Shalya Tantra Surgery in Ayurveda | सीसीआरएएस | 2020 | 1200 | – | मैं | 10 |
| 70 | Text Book of Shalya Tantra Surgery in Ayurveda | सीसीआरएएस | 2021 | 4550 | – | II | 0 |
| 71 | Training Module for Geriatric Health Care | ANHFW | 2008 | 100 | – | – | 0 |
| 72 | Tribal Health Care Research Andaman & Nicobar Islands) | सीसीआरएएस | 2010 | 300 | – | – | 13 |
| 73 | Tribal Health Care Research Kamrup Dist, Assam | सीसीआरएएस | 2008 | 300 | – | – | 9 |
| 74 | Vaidya Chikitsa Saar – HINDI Purvadha | सीसीआरएएस | 2008 | 400 | मैं | – | 10 |
| 75 | Vaidya Chikitsa Saar – HINDI Utharadha | सीसीआरएएस | 2008 | 400 | II | – | 10 |
| 76 | Vaidyaka prayoga vignanamu | सीसीआरएएस | 2007 | 213 | – | 11 | |
| 77 | Woman and Child Health Care Through Ayurveda | सीसीआरएएस | 2009 | 225 | – | – | 7 |
Suo Moto Disclosure and Activities : कैप्टन श्रीनिवास मूर्ति केंद्रीय आयुर्वेद अनुसंधान संस्थान, चेन्नई
Employee Details
Contact details:
Phone : 044-26214823 , 044-26207566
E-mail : csmcari@ccras.nic.in , csmdria@gmail.com
Address :
Assistant Director In-Charge,
Captain Srinivasa Murthy Central Ayurveda Research Institute
केंद्रीय आयुर्वेदिक विज्ञान अनुसंधान परिषद (सीसीआरएएस)
आयुष मंत्रालय, भारत सरकार
A.A. Government Hospital Campus, Arumbakkam, Chennai: 600 106
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