Dr. Malayamarutham Kalyankumarraju

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Dr. Malayamarutham Kalyankumarraju, is post graduated from Department of Pharmacology and Toxicology (Discipline: Regulatory Toxicology) of National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Mohali, Punjab and completed his Doctor of Philosophy in Pharmacology and Toxicology from Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Guwahati.

He joined as Assistant Research Officer (Pharmacology) in the year 2021 at Central Ayurveda Research Institute, Kolkata under Central Council for Research in Ayurvedic Sciences, New Delhi. He has been carrying out safety and efficacy studies using Preclinical models on Ayush drugs, formulations and Medicinal plants.

ONGOING PROJECTS:

1. Evaluation of acute dermal toxicity, 90 days repeated dose dermal toxicity, analgesic and anti-inflammatory activity of AYUSH MML Oil in rodent model.

2. Evaluation of effect of AYUSH M3 and Prabhakar vati on cardiovascular parameters. (Collaborative project with CSIR-CDRI, Lucknow).

3. Aqueous and Hydroalcoholic Extraction of selected Anukta Dravya Plants and Evaluation of their Therapeutic efficacy for various diseases. (Collaborative project with Sambalpur University, Odisha).

RESEARCH ARTICLES:

1. Hota, S.S., Sahoo, D.R., Pattnaik, S., Mishra, M., Mishra, T., Sahu, T., Naik, B.B., Kalyankumarraju, M., Dixit, A.K., Lamba, D. and Kumar YR, S., Naik, P. K*. Antioxidant, antibacterial and antibiofilm activities of Pittosporum napaulense (DC.) against drug-resistant Staphylococcus aureus and Shigella sp. Natural Product Research. 2024 38; pp.1-9. doi.org/10.1080/14786419.2024.2410422.

2. Kalyankumarraju, M., Puppala, E.R., Ahmed, S., Kumar, G.J., Tene, K., Syamprasad, N.P., Sahu, B.D., Barua, C.C. and Naidu, V.G.M*. Zanthoxylum alatum Roxb. seed extract ameliorates stress aggravated DSS-induced ulcerative colitis in mice: Plausible role on NF-κB signaling axis. Journal of Ethnopharmacology, 2021 279; p.114385. doi.org/10.1016/j.jep.2021.114385.

3. Tene, K., Kalyan Kumar, M., Basveshwar, G., Eswara Rao, P., Jagadeesh Kumar, G., Kumar, P., Pemmaraju, D.B., Murty, U.S.N., Gogoi, R. and Naidu, V.G.M*. Polyphenolic-rich compounds from Dillenia pentagyna (Roxb.) attenuates the doxorubicin-induced cardiotoxicity: a high-frequency ultrasonography assisted approach. Frontiers in Pharmacology. 2021 12; p.624706. doi.org/10.3389/fphar.2021.624706.

4. Tene, K., Kumar, K., Pemmaraju, D.B., Kumar, J., Shantanu, P.A., Gogoi, R. and Naidu, V.G.M*. Ameliorative effect of Dillenia indica fruits against doxorubicin-induced cardiomyocyte toxicity. Advances in Traditional Medicine. 2021 21; pp.805-814. doi.org/10.1007/s13596-020-00510-1.

5. Karnam, K.C., Ellutla, M., Bodduluru, L.N., Kasala, E.R*., Uppulapu, S.K., Kalyankumarraju, M. and Lahkar, M. Preventive effect of berberine against DMBA-induced breast cancer in female Sprague Dawley rats. Biomedicine & Pharmacotherapy. 2017 92, pp.207-214. doi.org/10.1016/j.biopha.2017.05.069.

BOOK CHAPTERS:

Published (Co-author):

1. Galgatte, U*., Gharat, P., Pulichera, Y., Kalyankumarraju, M.

Chapter: Molecular mechanism of bioactive compounds

Book: Futuristic Trends in Herbal Medicines and Food Products, IIP Series. Editor: Rahul Maurya.

Publisher: Iterative International Publishers; India, 2024. ISBN: 978-93-5747-680-5

Accepted (Shared First author by equal contribution):

1. Malayamarutham Kalyankumarraju*, Sudipto Debnath*, Amit Kumar Dixit, Gajji Babu

Chapter: CLINICAL USES OF INORGANIC AND ORGANIC NANOPARTICLES IN METABOLIC SYNDROME

Book: Nanobiomaterials and Nanomedicines for Metabolic Disorders                   Publisher: Elsevier