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Clinical Research

Clinical Research

Clinical Research Projects – IMR

List of completed projects during 2023-24 (April, 2023 to July, 2023)

Completed Clinical Research Projects – IMR
 1Evaluation of AYUSH-SR Tablet in occupational stress among Nurses – a randomized double blind placebo controlled clinical study.
 2Clinical evaluation of Gokshuradi Guggulu and Nimbadi Churna in Vatarakta (Gout)
List of ongoing projects – IMR
 1Randomised placebo controlled double blind clinical trial on the efficacy of AYUSH MANAS in the management of Smriti Dourbalya (Cognitive deficit)
 2Clinical Evaluation of Triphala Ghrita as topical (Tarpana) and internal medication in the management of Dry Age Related Macular Degeneration Symptoms.
 3Efficacy of Ayurvedic intervention in the management of occupational stress among IT professionals.
 4Evaluation of efficacy and safety AYUSH M-3 in the management of Pre-Hypertension – A double blind randomized control clinical study
 5Effectiveness of the role of Astangalavana and Srikhandasava as add on treatment on Madatyaya (Alcohol Dependence) – An Open Label Clinical Trial
 6Clinical evaluation of Vidanga churna and Vyoshadi Guggulu in the management of Medoroga (Obesity)
 7Clinical evaluation of Khadirarishta, Kaishor guggulu and Gandhakadya Malahar in the management of Vicharchika (Eczema)
8Evaluation of efficacy and safety of AYUSH-HR in the management of Pre-Hypertension – a double blind randomized control clinical study.
 9Clinical efficacy and safety of Arogyavardhini vati and Pippalyasava in the management of Non-Alcoholic Fatty Liver Disease (NAFLD) – An open label prospective clinical trial.
10A randomized, Placebo-controlled, Double blind clinical trial to evaluate the effect of Trikatu in Subclinical Hypothyroidism.
11Impact of Ayurveda Based Lifestyle Advocacy and Practices among apparently healthy individuals across selected cities in India – A Randomized Parallel Group Study
12Clinical Evaluation of Lekhaniya Gana Kashaya and Arogyavardhini Gutika in the management of Medoroga (Obesity)
13Efficacy and safety of Ayurveda Formulation ‘Trikatu’ in Dyslipidemia – A Prospective Randomized Double Blind Placebo Controlled Trial
14Clinical evaluation of Lashunadi Vati and Pippaladyasava in the management of Agnimandya
15Clinical assessment of the efficacy of Ayurvedic management in PCOS – A randomized open label control trial.
16A Clinical Consensus Study for Developing the practice guidelines of Marsa Nasya Karma with a multi-center Feasibility Study in Cervical Spondylosis
17Clinical evaluation of Nimbadi Churna, Khadirarista and Arjuna Lepa in the management of Acne (Yuvan Pidika)
18Knowledge, Attitude, and Practice (KAP) towards Swarnaprashana among Ayurveda Practitioners: A cross-sectional Survey

Collaborative Clinical Research

Completed Clinical Research Projects – Collaborative
 1A comparative clinical study of Ayush LND a coded Ayurvedic formulation in the management of Asrigdara (Abnormal Uterine Bleeding)
 2A Randomized controlled trial to evaluate the efficacy of Marma therapy in Lumbar disc Herniation with Radiculopathy.

List of ongoing projects

1A phase II trial to study efficacy, toxicity and imunomodulatory effect of Carctol-S in high grade serous epithelial ovarian cancer at first serological relapse collaborative project.
2Randomized double blind placebo controlled clinical study Ayurvedic coded drug AYUSH-A in the management of Bronchial Asthma (Tamaka Shwasa)
Evaluation of Hepatoprotective activity of PTK as an add on therapy in the patients of Tuberculosis on ATT –  A double blind randomized control clinical study
4Study the physiological basis and gut bacterial modulation induced by Virechana Purgation therapy in the healthy adults: A prospective longitudinal study.
5A study of Ashwagandha administration in participant vaccinated against COVID-19 on safety, immunogenicity and protection: A randomized, double blind placebo controlled multi-centric clinical trial.
6Evaluating the efficacy of Ayurvedic intervention as add on to conventional treatment and explore the interaction of epigenetics, neuro/gut biomarkers and neuroimaging in pediatric ADHD (Attention Deficit Hyperacidity Disorder)
7Prospective double blind randomized controlled clinical study on Ayurvedic intervention (Sarpagandha Mishran) vs. Amlodipine in the management of stage-I Primary Hypertension
8Double blind randomized placebo controlled multicentric clinical trial of Ayush M-3 in the management of Migraine.
9Evaluation of Ayush-GMH in the subjects of mild to moderate Non alcoholic fatty liver disease (NAFLD)-A double blind randomized control clinical study
10A randomized trial to evaluate the efficacy of multimodal Ayurveda interventions in Jannu Sandhigatavata (Primary Knee – osteoarthritis)
11A pilot study to assess the effect of intranasal oil instillation (Pratimarsha Nasya) on nasal barrier function among healthy individuals
12A double blind, double dummy prospective randomized controlled study to evaluate the efficacy of classical Ayurveda management versus Methotrexate in Rheumatoid Arthritis.
13Ayurveda therapeutic regiman as on Add-on to optimized conventional management of Parkinson’s disease: an RCT for assessment of clinical Cortical excitability neuroimmune and Autonomic function parameters.
14Efficacy of Ayurveda nutritional supplements and Yoga protocol in the prevention and reduction of the severity of Acute Mountain Sickness: an open-label randomized controlled study
15A Randomized Controlled Study to Assess the Effect of Marsha Nasya Karma in Motor, Sensory, Memory and Cognitive Parameters elicited through f – MRI in Apparently Healthy Individuals

COVID-19 related Research initiatives

CCRAS has undertaken 6 research studies on COVID-19 include prophylactic studies, interventional studies (on COVID-19 and post COVID), observational study, survey study and systematic review through Intra-mural research and collaborative research mode through its peripheral institutes out of them, 3 have been completed and 3 research studies are going on.

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